I fucking love the Krebs cycle. It’s so cool. Something I love is that on the big Roche Biochemical Pathways poster, if you zoom out, you can see the Kreb’s cycle in the centre. It’s so cool at how it is so central to cell metabolism. It’s obviously key in carbohydrate metabolism, but it also acts as the entry point for the metabolites formed from the breakdown of amino acids and fatty acids.
Here’s a zoomed out view (low res, you can’t zoom in):
The interactive website is down at the moment, but a high res image can be found here
Remember my biochem professor showed that chart at the end of “Biochem 100” We had focused in citric acid cycle, the electron transfer in the mitocondria, basic genetics (amino acids, RNA, DNA), neogluconesis, and something about removing nitrogen from cells +a whole lot more I can’t remember 20 years after the class.
I ended up doing physical chemistry doing my master thesis on thermodynamics in enzymes. Only a couple of formulas and four laws that is already well defined. Way easier than this
I almost fear asking what “Part 2” entails in the roche version
OMG not the Krebs cycle! Can we do Linux From Scratch instead?
Compromise on Krebs cycle from scratch?
How about the Citric Acid Cycle then?
If you just asked without the gun, it would have been an enthusiastic yes. Trust your choices dammit.
It’s just covers different topics; it’s titled “Cell and molecular processes”. I don’t find it as fun as a topic, and it’s also far less comprehensive than the metabolic pathways one (possibly because cell biology is more complex and thus it’s much harder to capture all that we know at a given time)
Crabs cycling around
Fun fact: “Krebs” is German for “crab”.
Whaaaat…
Is it called the Krebs Cycle because the diagram looks like a crab?
Nah, the guy who discovered it was called Hans Krebs: https://en.wikipedia.org/wiki/Hans_Krebs_(biochemist)
Oh yeah, that makes a lot of sense. Thanks for the knowledge, friend.
No! Not again, I’ve already learned it three times already! 😭
I can fix her! And I get to learn about the Krebs cycle too? 10/10 date!
Hell yeah
Grade 11 again?
Studying the Krebs cycle never ends, it just begins
I studied biology but somehow completely dodged the Krebs cycle. Memorizing technical terms never really was my passion so I didn’t really mind.
Fuck the Krebs👎
You got another source of ATP? Can you hook a brother up?
My favorite citric acid cycle fact is that cancer cells often just stop doing it. Something in the pentose shunt pathway provides a critical metabolite, because just about every cancer mass you’ll find is busy with ‘not’ the citric acid cycle and is kicking out those products. My cancer biology professor didn’t really have a good answer as to why (it wasn’t his specialty, he just got told to teach it, lol).
