The difference is not my point at all.

If my brother, at a very young age, had made the reasonable decision of pursuing higher education as a path in life, and due to a wide variety of circumstances is in financial trouble and I could help…

Guess what, I’m helping. I do not give a fuck if there’s a difference, my guy. And I also know my brother would stop in the middle of a career defining work meeting and come rescue me if I was in trouble.

And I wouldn’t trade that kind of relationship for your world view.

If that’s how you see our familiar relations sure, you’re your own individual. But boy I’d hate to be your family member.

Maybe my phrasing was a bit accidentally misleading - when I mentioned they are where everyone wants to study at or the ones publishing the most research, I meant locally, for Brazilians and to some extent our LATAM neighbors.

That’s why you probably never heard of them by name, they don’t carry the weight of an “Oxford” or “Tokyo University”.

That said, you absolutely interacted with fruits of their research. The term “ultra processed food” comes from the University of São Paulo and their research.

Decisions have consequences

I’d still help you out if you were in a car crash, even though it was your decision to drive a vehicle.

Though of course, this doesn’t mean helping out is mandatory.

The best universities in Brazil, the ones everyone wants to study at and the ones producing cutting edge research… Are all free, they’re public universities. The private ones can’t compete on most metrics.

So yeah, maybe americans should drop the whole “first world” tag to pretend they’re special and rebalance their priorities.

Nooo I did not need to hear that

The Docked performance doesn’t really matter. If you’re going to worry about a docked device, just use a regular PC + a long HDMI cable or HDMI over CAT6 converter.

It’s so sad such illiteracy means people like you associate the dash with AI

You can repeat “no harm done” at the end of every comment, and it wouldn’t change any of the data we have proving it does, in fact, a lot of harm

You can’t compare prohibition in a broad context to restrictive usage.

You can’t drive a vehicle in the sidewalk either, doesn’t mean you’re forbidden to have a car.

Have your phone - download TikTok, Canva, Wikipedia, WhatsApp, go nuts… Outside of a classroom.

That’s how you get genital fungi

Other Sunni schools of jurisprudence rely on early Islamic scholars who state that a fetus can “sleep and stop developing for 5 years in a womb”

Glad to hear this justice system is so smart, well developed and based on ground realities!

Maybe not directly for “being too Western” but certainly it’s the one providing the moral framework for allowing murder for ideological and behavioural differences.

That’s a fantastic question… which is exactly what I’m pursuing in my master’s degree right now :). The goal will be to have a full metabolic map showing all the involved genes and how they interact, when they’re triggered (and by which signaling pathways) and how it all comes together for placental development.

Basically, yes. Viruses came up with the syncitins to fuse with host cells, then when they infected us and integrated their genome we had the code for making these proteins… and turns out “invading tissue” was a really useful tool for the embryo.

Happily! Basically, the true placenta we mammals (Eutheria) have is what allows such a long gestation period. Unlike our closely related marsupials, that quickly deplete their resources and must give birth, our placenta allows for a continuous exchange of nutrients. This involves a quite complicated process of embryonic tissue invading the uterine wall, so you can imagine the kind of immunological regulation that must be taking place for that to work.

So you’d assume we have several genes highly specific to our placenta that appear when we Eutherians first appeared… right? No! Turns out the vast majority already existed in jawed vertebrates (our common ancestor with sharks), then quite a lot show up in bony fish (our common ancestor with most things you call fish), and just one shows up in Tetrapoda (our common ancestor with amphibians).

So most of the framework for developing an organ such as the placenta already existed for millions of years, so what exactly was missing before it could finally show up in evolutionary history? The two genes that are absolutely required for this whole crazy “let’s invade the mother’s uterine wall tissue but NOT trigger her immune system” part: CSF2 and a group of closely related genes called syncitins.

Syncitins are the star here, because they’re actually a gene that came from ancient retroviruses. In the virus, they were expressed in the envelope and controlled the fusion between the viral particle and the host cell. These viruses got integrated into our genome, and this “fusion with the host cell” mechanism became extremely useful and crucial for the placenta, basically allowing it to exist.

It works in the same way that dumping your GameCube games and running them on Dolphin works… It’s quick and easy, but it’s against the ToS and requires breaking DRM.

Steam’s DRM is weak, and in some interviews some Valve developers even gave hints that this is on purpose. Many Steam games will simply run without Steam if you just double click the .exe in the install folder, and the vast majority that only rely on Steam’s DRM can be opened by running a free “Steam Emulator” software that pretends to be an active Steam account with a correct license.

While you’re not wrong, by that logic, it’s actually fairly trivial to take my Steam downloads drive and run it on any computer even without my Steam account.

Mammals wouldn’t have a chorioallantoic placenta at all if not for a virus integrated into our genome. Mapping when in evolution the genes responsible for placental development first appeared was my first participation in scientific research, so I love this topic.

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