I haven’t tested out the PS4 emulators myself yet,
due to them still being in their infancy, so I’m not expecting great play-ability yet.

shadPS4 currently is the most promising PS4 emulator though,
in their FAQ they mention the minimum system requirements:

• https://github.com/shadps4-emu/shadPS4
• https://shadps4.net/index.php/faq/

However, these requirements likely will not suffice / appear very low to me,
which they also do mention in their FAQ.

Also, if you’re interested,
I’ve collected all the open source emulators which I know of
and/or used in the past in a Github list (currently has 111 entries):
https://github.com/stars/Rikj000/lists/emulation

Nearly all of them.

A better question would be,
which systems can not yet be emulated on PC.

E.g.

• PS4 emulation is still in it’s infancy stage,
  barely runs games, and has high demands
• PS5 emulation does not exist yet afaik

Afaik Qubes runs all software in containers,
which isolates them from each other,
which is great for privacy.

However, OP only asked for Chrome,
and I assume the jump to Qubes might be too big.

To only isolate Chrome,
I’d recommend a Flatpak instead.

Or even better Ungoogled-Chromium.