• SpezCanLigmaBalls@lemmy.world
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    11 months ago

    Oh wtf this was one of the drugs people used to poison themselves with? I was prescribed this a month ago because the rheumatologist told me is the safest drug for auto immune issues although I still need to take mehtylprednisolone every few months due to spinal inflammation that messes with nerves.

    • Kecessa@sh.itjust.works
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      11 months ago

      It’s great if it’s used to treat what it was meant to, people started taking it because a few doctors mentioned it might help with COVID without having any proof it did.

    • Wrench@lemmy.world
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      11 months ago

      Just like Ivermectin, it has a legitimate use. But snakeoil salesmen peddled both of them as off label Covid miracle cures with zero medical trials, or even an attempt to begin one.

    • dantheclamman@lemmy.worldOP
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      11 months ago

      The hazards here were related to passing around doses, improper prescriptions from disreputable doctors, and not seeking out actual treatments for covid. If you have certain conditions and medications there can be side effects and interactions that harm health, but that your doctor should have considered. Some people who really needed hydroxychloroquine for legitimate uses like yours had trouble getting it because of shortages due to morons rushing out to get it.

    • marcos@lemmy.world
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      11 months ago

      If you take a look at the more dangerous collateral effects… and correlate with the more dangerous COVID effects, you’ll have a surprise.

      By itself, the drug is pretty safe.

  • Socsa@sh.itjust.works
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    11 months ago

    But I’m not allowed to add caffeine powder to my yogurt anymore because one idiot died 🙄

  • TempermentalAnomaly@lemmy.world
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    11 months ago

    The amount of people not reading the article or the study is astounding.

    This is not about Trump.
    This is not about your conservative uncle.
    This is not about America only.

    This is about off label prescribing in ICU and ERs early in the pandemic with low evidence (theoretical pathways) in six countries which either gave explicit approval or unclear guidance that was interpreted as approval. It goes on to suggest that in a similar emergency future, the state agencies sould do better.

    In the absence of restriction, the number of expected HCQ-related deaths is likely to be directly related to the promotion of its prescription by scientists, physicians and health agencies. In February and March 2020, the use of this treatment was widely promoted based on preliminary reports suggesting a potential efficacy against COVID-19 [80]. For instance, the use of HCQ markedly increased from mid-March to mid-April 2020 [81], [82] in France before a temporary recommendation supporting its use by the State Council was rapidly rejected [83]. Similarly, the Food and Drug Administration (FDA) granted a temporary emergency use authorisation for HCQ on March 28th 2020, which was finally revoked on June 15th 2020 [84]. In India, HCQ was also prescribed as a curative treatment to patients with COVID-19 and as a prophylactic treatment for front-line workers based on public authority guidance [85]. Conversely, the British government promoted HCQ use only within clinical trials, explaining the absence of cohort studies reporting the use of HCQ in the United Kingdom in the present study [86]. Consistently, a cohort of a multinational network showed a wide variation in the use of HCQ between countries, with 85% in Spain, 14% in the USA and less than 2% in China [80]. The rush to administer this treatment caused supply shortages in community pharmacies, forcing the implementation of dispensing restrictions [82]. Finally, the results of observational studies and randomized trials in May and June 2020, respectively, convincingly demonstrated that HCQ was ineffective and led to an increase in adverse events [4], [5], [12], [66], [73].

    • cley_faye@lemmy.world
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      11 months ago

      This is the main point : the breach of the trust we could have in state agencies and doctors. Hopefully the lesson stick this time.

  • BigMacHole@lemm.ee
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    11 months ago

    That’s more then all Vaccines COMBINED! Don’t let our Kids get Vaxxed! Hydrochloroquine them instead!

  • Gazumi@lemmy.world
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    11 months ago

    Donald Trump should be charged for those deaths. Sadly, it is unlikely that the families that took his advice would take out a class action. As to his comment about what have you got to lose? The court or any reasonable party simply has to read the patient information leaflet.

  • FontMasterFlex@lemmy.world
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    11 months ago

    “COULD HAVE”

    I’m so sick of this sort of reporting. Too many “maybe”, “might have”, “could be”. it’s just fear mongering.

    • dantheclamman@lemmy.worldOP
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      11 months ago

      ‘Could have’ is due to the range of potential estimates. The confidence interval was between 6420–20294 deaths.

  • afraid_of_zombies@lemmy.world
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    11 months ago

    So looks like my city will get some snow this weekend. That should be fun. The holidays kinda wiped me out and looking to hang around the house. What’s new with you guys?