At this point I’m trying to get off my antidepressant because I think it’s suppressing a lot of the mood changes I would have otherwise gotten from starting estrogen. So far it seems like my guess is correct; every time I step down a dose my feelings get stronger, I feel less dissociated, and so forth. It’s a double edged sword though. I’ve had some moments of extreme dysphoria while my brain is getting used to the lower dosage.